"Monster Cell Lymphoma or Plasma Cell-rich AFX or.....?"

71-y-o female. Symmetrical, rapidly (12 months) grown, smooth-surfaced reddish tumor over right temple.
Clinical diagnosis: Carcinoma.
Macroscopically and in scanning magnification symmetrical, sharply circumscribed exophytic tumor with flat bottom.

Part I: H&E + Giemsa (12 pictures)
Part II: Immunohistochemistry (12 pictures)
Part III: Immunohistochemistry (12 pictures)

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Note: Many bizarre cells without any significant immunophenotype. These cells are mitotically active (MPM2/ anti-topoisomerase 2 alpha).
Many polyclonal plasma cells. Noteworthy: KiM1p overexpressed but CD68 (PGM-1) rather inconspicuous.

Dermatohistopathologische Gemeinschaftspraxis
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Fax : ++49/7541 / 6044-10

e-mail:  dermpath@dermpath.de

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